IBM Systems Magazine, Power Systems - February 2018 - 45

Say a patient goes to the doctor for a PSA (Prostate-Specific
Antigen) prostate cancer screening,
which typically has a high rate
of false positives. Many people
get frightened if they may have
elevated PSA levels, but it shouldn't
really be an immediate cause for
concern because other factors will
instead indicate that the prostate
isn't cancerous. Maybe the prostate
is just inflamed. So the question is,
can we find a marker that complements or maybe replaces PSA tests
and is more specific and sensitive?
ISM: How does the physics
of fluids play into this new
work?
GS: Exosomes have been found in
virtually every fluid in the body,
therefore the physics of fluids
can play an important role in
separating the different components, including exosomes, from
those fluids. As it turns out, the
nanoDLD lends itself very well
to separating, identifying and
quantifying exosomes from fluid
samples. There are technical
difficulties with the isolation of
exosomes in that they're very
small, and we believe our technology can solve those difficulties.
When it does, we'll make big step
towards using exosomes in a
platform that could be used at the
doctor's office, which would make
a big contribution towards liquid
biopsy analysis.
ISM: So this will be used in
clinical settings?
GS: That's the idea and vision
behind what we're doing: A
person goes to a doctor and gives
a blood or urine sample. This
sample then goes into our device,
where the solution gets processed
in such a way that the exosomes
are separated and interrogated
with respect to the markers they
have. In the best case, you don't
have any markers that should

be of concern. In the worst case,
a few markers show levels that
are in a range that indicates
that we should do more testing.
So the advantage of this is that
you could look at many markers
simultaneously corresponding

to several cancers or even other
diseases in the same assessment
very fast and cheap.
ISM: How quickly would the
results come back?
GS: Ideally, within hours. So

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Table of Contents for the Digital Edition of IBM Systems Magazine, Power Systems - February 2018

Table of Contents
Editor's Desk: From Here to AI
IBM Perspective: Hitting the Infrastructure Wall
Techbits: Breaking the Tape (Record), Plastic Fantastic, A Tale of Five Cities
Trends: A Human-Centric Approach: IBM Design Thinking leads to an elevated user experience
Partner POV: What I've Learned: 5 lessons from 25 years of IBM i experience
Case Study: It's in the Bag: How Imperial Bag & Paper Co. has eased the growing pains associated with increasing its market share
Cover Story: Optimize Your AI Journey: IBM Power hardware and software streamline deep learning initiatives
Feature 1: Build a Better AI Workflow: Start with a strong foundation
Feature 2: A Plan in Place: Determine which of the 7 levels of buisness continuity is right for you
TECH Showcase: Taking Action on Modernization: Updating computing environments is a manageable task that provides long-term benefits
R&D: Testing Healthcare: IBM Research and partners are focusing on nanoscale cancer testing that could save lives
Solutions: NowYouSign, Power i4 Solutions; Managed Resilience Service, Vision Solutions Inc.
Snapshot: Kevin Fugate
Reference Point - Global Events, Education, Resources for Power Systems
2018 Power Systems Solution Edition Index
IBM Systems Magazine, Power Systems - February 2018 - Intro
IBM Systems Magazine, Power Systems - February 2018 - Cover1
IBM Systems Magazine, Power Systems - February 2018 - Cover2
IBM Systems Magazine, Power Systems - February 2018 - 1
IBM Systems Magazine, Power Systems - February 2018 - Table of Contents
IBM Systems Magazine, Power Systems - February 2018 - 3
IBM Systems Magazine, Power Systems - February 2018 - Editor's Desk: From Here to AI
IBM Systems Magazine, Power Systems - February 2018 - CT1
IBM Systems Magazine, Power Systems - February 2018 - CT2
IBM Systems Magazine, Power Systems - February 2018 - IBM Perspective: Hitting the Infrastructure Wall
IBM Systems Magazine, Power Systems - February 2018 - Techbits: Breaking the Tape (Record), Plastic Fantastic, A Tale of Five Cities
IBM Systems Magazine, Power Systems - February 2018 - 7
IBM Systems Magazine, Power Systems - February 2018 - 8
IBM Systems Magazine, Power Systems - February 2018 - Trends: A Human-Centric Approach: IBM Design Thinking leads to an elevated user experience
IBM Systems Magazine, Power Systems - February 2018 - Partner POV: What I've Learned: 5 lessons from 25 years of IBM i experience
IBM Systems Magazine, Power Systems - February 2018 - 11
IBM Systems Magazine, Power Systems - February 2018 - Case Study: It's in the Bag: How Imperial Bag & Paper Co. has eased the growing pains associated with increasing its market share
IBM Systems Magazine, Power Systems - February 2018 - 13
IBM Systems Magazine, Power Systems - February 2018 - 14
IBM Systems Magazine, Power Systems - February 2018 - 15
IBM Systems Magazine, Power Systems - February 2018 - 16
IBM Systems Magazine, Power Systems - February 2018 - 17
IBM Systems Magazine, Power Systems - February 2018 - Cover Story: Optimize Your AI Journey: IBM Power hardware and software streamline deep learning initiatives
IBM Systems Magazine, Power Systems - February 2018 - 19
IBM Systems Magazine, Power Systems - February 2018 - 20
IBM Systems Magazine, Power Systems - February 2018 - 21
IBM Systems Magazine, Power Systems - February 2018 - 22
IBM Systems Magazine, Power Systems - February 2018 - 23
IBM Systems Magazine, Power Systems - February 2018 - Feature 1: Build a Better AI Workflow: Start with a strong foundation
IBM Systems Magazine, Power Systems - February 2018 - 25
IBM Systems Magazine, Power Systems - February 2018 - Feature 2: A Plan in Place: Determine which of the 7 levels of buisness continuity is right for you
IBM Systems Magazine, Power Systems - February 2018 - 27
IBM Systems Magazine, Power Systems - February 2018 - 28
IBM Systems Magazine, Power Systems - February 2018 - 29
IBM Systems Magazine, Power Systems - February 2018 - 30
IBM Systems Magazine, Power Systems - February 2018 - 31
IBM Systems Magazine, Power Systems - February 2018 - 32
IBM Systems Magazine, Power Systems - February 2018 - TECH Showcase: Taking Action on Modernization: Updating computing environments is a manageable task that provides long-term benefits
IBM Systems Magazine, Power Systems - February 2018 - 34
IBM Systems Magazine, Power Systems - February 2018 - 35
IBM Systems Magazine, Power Systems - February 2018 - 36
IBM Systems Magazine, Power Systems - February 2018 - 37
IBM Systems Magazine, Power Systems - February 2018 - 38
IBM Systems Magazine, Power Systems - February 2018 - 39
IBM Systems Magazine, Power Systems - February 2018 - 40
IBM Systems Magazine, Power Systems - February 2018 - 41
IBM Systems Magazine, Power Systems - February 2018 - 42
IBM Systems Magazine, Power Systems - February 2018 - R&D: Testing Healthcare: IBM Research and partners are focusing on nanoscale cancer testing that could save lives
IBM Systems Magazine, Power Systems - February 2018 - 44
IBM Systems Magazine, Power Systems - February 2018 - 45
IBM Systems Magazine, Power Systems - February 2018 - 46
IBM Systems Magazine, Power Systems - February 2018 - Solutions: NowYouSign, Power i4 Solutions; Managed Resilience Service, Vision Solutions Inc.
IBM Systems Magazine, Power Systems - February 2018 - Snapshot: Kevin Fugate
IBM Systems Magazine, Power Systems - February 2018 - Cover3
IBM Systems Magazine, Power Systems - February 2018 - Cover4
IBM Systems Magazine, Power Systems - February 2018 - Reference Point - Global Events, Education, Resources for Power Systems
IBM Systems Magazine, Power Systems - February 2018 - 2018 Power Systems Solution Edition Index
IBM Systems Magazine, Power Systems - February 2018 - SE2
IBM Systems Magazine, Power Systems - February 2018 - SE3
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http://www.nxtbook.com/nxtbooks/mspcomm/ibmsystems_power_200901
http://www.nxtbookMEDIA.com