IBM Systems Magazine, Power Systems edition - August 2014 - 32

TRENDS

Orchestrator distinguishes
itself from scripted workflow
tools with its capability to handle
complex workflow dynamically-
individual workloads or jobs
can be defined through a userfriendly interface, incorporating
variables, parameters and data
definitions into a standard
template. The workload manager
will transparently handle

the submission, placement,
monitoring and completion
of each job. Workflow engine
connects jobs in linear
progression, conditional branches
or loops based on user-defined
criteria and requirements for
completion and advancement.
To maximize the throughput
of the workflow for genomics
sequencing analysis, a special

IBM Solution for Genomic Workflow
Acceleration-Power Systems Edition
In deep collaboration with IBM clients and across multiple disciplines, IBM
Solution for Genomic Workflow Acceleration-Power Systems* Edition was
designed by bioinformatics experts and technologists to accelerate the
end-to-end analysis, storage and sharing of genomics data and hardened
with widely used bioinformatics applications and pipelines. Designed for
ease-of-use, this high-throughput platform delivers fast turnaround for a
variety of workflows including genomic medicine, agrigenomics, biofuels,
forensics and drug development.
The task of discovering subtle patterns and variations in molecular biology,
in many fields of study ending in -omics, such as genomics or proteomics,
represents a grand compute and storage challenge. This reference platform tackles these challenges by seamlessly integrating Next Generation
Sequencing systems with a scalable and high-performance compute infrastructure. Upon completion of sequencing, raw data will be written directly
into high-performance Elastic Storage (Datahub) for ready access by hybrid
compute infrastructure. The computational and analytic process then can be
designed into simplified and automated workflows, capturing and protecting
repeatable best practices (Orchestrator). Workflow steps and dependencies
are managed within an intuitive GUI, providing a fast-path to automating
lengthy, repetitive tasks highly prone to human error. These adaptable
workflows become self-documenting, so the process updates can be made
and tracked easily. This platform also features a library of sample workflows
based on best practices to accelerate deployment, fully exploit available
compute and storage resources, and reduce time to discovery. These sample
and other user-defined workflows can be made available for collaboration
through an enterprise portal (AppCenter).
This integration of high-performance storage, workflow orchestration and
portal access is available today as part of the offering with guided steps
for the implementation and deployment. This predefined platform was
designed to manage hybrid environments, including Power* and x86-based
workloads, and can also be easily adapted to support large scale and
cloud based deployments.
For more information, visit www.ibm.com/systems/power/solutions/industry/
healthcare.html

type of workload can be defined
by using job arrays so data can be
split and processed by many jobs
in parallel.
In another innovative use
case for genomics processing,
multiple subflows can be defined
as a parallel pipeline for variant
analysis following the alignment
of the genome. The results from
each subflow are then merged
into a single output and provide
the analyst with a comparative
view of multiple tools or settings.
The workflow can also be
designed as a module and
embedded into larger workflows
as a dynamic building block. Not
only will this approach enable
efficient building and reuse of the
pipelines, it will also encourage
collaborative sharing of the
genomic pipelines among a group
of users or within larger scientific
communities.
As more institutions are
deploying hybrid cloud solutions
with distributed resources,
Orchestrator can coordinate the
distribution of workloads based
on data localities, predefined
policies, thresholds and real-time
input of resource availabilities.
For example, a workflow can be
designed for processing genomic
raw data closer to sequencers, and
followed by sequence alignment
and assembly using MapReduce
framework on a remote big data
cluster. In another use case, a
workflow can be designed to
launch a proxy event moving
data from a satellite system to
a central HPC cluster when the
genomic processing reaches 50
percent of the completion rate. The
computation and data movement
can happen concurrently to save
time and cost.

Manage Global Access
With AppCenter
In the reference architecture,
IBM also defines a capability

32 // AUGUST 2014 ibmsystemsmag.com

pg 30-33.indd 4

7/28/14 9:22 AM


http://www.ibm.com/systems/power/solutions/industry/healthcare.html http://www.ibm.com/systems/power/solutions/industry/healthcare.html http://www.ibmsystemsmag.com

IBM Systems Magazine, Power Systems edition - August 2014

Table of Contents for the Digital Edition of IBM Systems Magazine, Power Systems edition - August 2014

Table of Contents
Editor's Desk: Killing cancer
IBM Perspective: Healthcare's grand challenge
Techbits: Shape-shifters in the sky
Partner PoV: An integration layer can beat rip-and-replace or custom code
Case Study: Fields of Dreams: MEDHOST accommodates growing healthcare providers with expanding field lengths
Cover Story: Paradigm Shift: How MD Anderson and Watson are transforming healthcare
Feature: Treating Healthcare’s Pain Points: IBM Watson pairs with Power Systems to bring new tools to medical service providers
Trends: IBM reference architecture for genomics brings power to research
R&D: The Watt-Sun program is poised to improve weather forecasting for solar energy
Solutions: Accelerator for .NET 5.0; Open Access for COBOL; Capture With Business-Items; Nitro AutoCode; Formtastic 5.4.5; Advanced Job Scheduler 12; Profound UI 5.0
Snapshot: Amy Hoerle
Reference Point - Global Events, Education, Resources for Power Systems
2014 Power Systems Solution Edition Product Index
IBM Systems Magazine, Power Systems edition - August 2014 - Intro
IBM Systems Magazine, Power Systems edition - August 2014 - Cover1
IBM Systems Magazine, Power Systems edition - August 2014 - Cover2
IBM Systems Magazine, Power Systems edition - August 2014 - 1
IBM Systems Magazine, Power Systems edition - August 2014 - Table of Contents
IBM Systems Magazine, Power Systems edition - August 2014 - 3
IBM Systems Magazine, Power Systems edition - August 2014 - 4
IBM Systems Magazine, Power Systems edition - August 2014 - Editor's Desk: Killing cancer
IBM Systems Magazine, Power Systems edition - August 2014 - IBM Perspective: Healthcare's grand challenge
IBM Systems Magazine, Power Systems edition - August 2014 - Techbits: Shape-shifters in the sky
IBM Systems Magazine, Power Systems edition - August 2014 - Partner PoV: An integration layer can beat rip-and-replace or custom code
IBM Systems Magazine, Power Systems edition - August 2014 - 9
IBM Systems Magazine, Power Systems edition - August 2014 - 10
IBM Systems Magazine, Power Systems edition - August 2014 - 11
IBM Systems Magazine, Power Systems edition - August 2014 - Case Study: Fields of Dreams: MEDHOST accommodates growing healthcare providers with expanding field lengths
IBM Systems Magazine, Power Systems edition - August 2014 - 13
IBM Systems Magazine, Power Systems edition - August 2014 - 14
IBM Systems Magazine, Power Systems edition - August 2014 - 15
IBM Systems Magazine, Power Systems edition - August 2014 - 16
IBM Systems Magazine, Power Systems edition - August 2014 - 17
IBM Systems Magazine, Power Systems edition - August 2014 - Cover Story: Paradigm Shift: How MD Anderson and Watson are transforming healthcare
IBM Systems Magazine, Power Systems edition - August 2014 - 19
IBM Systems Magazine, Power Systems edition - August 2014 - 20
IBM Systems Magazine, Power Systems edition - August 2014 - 21
IBM Systems Magazine, Power Systems edition - August 2014 - 22
IBM Systems Magazine, Power Systems edition - August 2014 - 23
IBM Systems Magazine, Power Systems edition - August 2014 - Feature: Treating Healthcare’s Pain Points: IBM Watson pairs with Power Systems to bring new tools to medical service providers
IBM Systems Magazine, Power Systems edition - August 2014 - 25
IBM Systems Magazine, Power Systems edition - August 2014 - 26
IBM Systems Magazine, Power Systems edition - August 2014 - 27
IBM Systems Magazine, Power Systems edition - August 2014 - 28
IBM Systems Magazine, Power Systems edition - August 2014 - 29
IBM Systems Magazine, Power Systems edition - August 2014 - Trends: IBM reference architecture for genomics brings power to research
IBM Systems Magazine, Power Systems edition - August 2014 - 31
IBM Systems Magazine, Power Systems edition - August 2014 - 32
IBM Systems Magazine, Power Systems edition - August 2014 - 33
IBM Systems Magazine, Power Systems edition - August 2014 - R&D: The Watt-Sun program is poised to improve weather forecasting for solar energy
IBM Systems Magazine, Power Systems edition - August 2014 - 35
IBM Systems Magazine, Power Systems edition - August 2014 - 36
IBM Systems Magazine, Power Systems edition - August 2014 - Solutions: Accelerator for .NET 5.0; Open Access for COBOL; Capture With Business-Items; Nitro AutoCode; Formtastic 5.4.5; Advanced Job Scheduler 12; Profound UI 5.0
IBM Systems Magazine, Power Systems edition - August 2014 - 38
IBM Systems Magazine, Power Systems edition - August 2014 - 39
IBM Systems Magazine, Power Systems edition - August 2014 - Snapshot: Amy Hoerle
IBM Systems Magazine, Power Systems edition - August 2014 - Cover3
IBM Systems Magazine, Power Systems edition - August 2014 - Cover4
IBM Systems Magazine, Power Systems edition - August 2014 - Reference Point - Global Events, Education, Resources for Power Systems
IBM Systems Magazine, Power Systems edition - August 2014 - 2014 Power Systems Solution Edition Product Index
IBM Systems Magazine, Power Systems edition - August 2014 - SE2
IBM Systems Magazine, Power Systems edition - August 2014 - SE3
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